PDF Emerging Technologies Powering Rare and Neglected Disease Diagnosis and Therapy Development Download
- Author: Zhichao Liu
- Publisher: Frontiers Media SA
- ISBN: 2889760642
- Category : Science
- Languages : en
- Pages : 206
eBook downloads, eBook resources & eBook authors
Genetic disorders have been the focus of scientists for a long time. The emergence of next-generation sequencing techniques has ushered a new era in genetics and several developments have occurred in human genetics. The scientific perspective has also been widened with omics technologies that allow researchers to analyze genetic sequences and their expression products. An integrated approach is being used not only for diagnosis but also for disease management and therapeutic purposes. This book highlights emerging areas of omics technology and its application in the diagnosis and management of human genetic disorders. The book covers three areas of research and implementation: 1) Diagnosis (covering conventional strategies to next-generation platforms). This section focuses on the role of in silico analysis, databases and multi-omics of single-cell which will help in designing better management strategies. 2) Disease Management and therapeutic interventions. This section starts with genetic counselling and progresses to more specific techniques such as pharmacogenomics and personalized medicine, gene editing techniques and their applications in gene therapies and regenerative medicine. 3) Case studies. This section discusses the applications and success of all the above-mentioned strategies on selected human disorders. This book serves as a handy reference for students and academics studying advanced omics techniques in biochemistry and molecular genetics as part of courses in life sciences, pharmacology and medicine.
s the rapid development of the world's economy brought serious environmental problems, the economy must accelerate industrial structure adjustment and development mode transformation to achieve sustainable development. A cleaner production mode based on cleaner technology is a crucial way to solve the conflict between economic growth and environmental protection effectively. In essence, cleaner production is a kind of production mode in which the environmental strategy of overall prevention is adopted for the production process to reduce or eliminate their possible harm to human beings and the environment while fully meeting human needs and maximizing social and economic benefits. Fossil energy and renewable energy have promoted the development of many emerging industries, such as the automobile industry, aerospace technology, modern production and processing, and modern transportation industry, and preventing waste production while increasing efficiencies in the uses of energy is a crucial issue. Specific measures include: • Using clean energy and raw materials; • Adopting advanced technology and equipment; • Comprehensive utilization; • Reducing pollution from the source; • Improving utilization efficiency; • Reducing or avoiding the generation and emission of pollutants in the process of production. This Research Topic aims to report the most important and latest technological advances in cleaner treatment technologies of fossil energy (such as oil and natural gas) and renewable energy (such as hydrogen energy and geothermal energy) and serves as a platform for addressing and discussing theoretical and practical cleaner production.
Dialectical behavior therapy (DBT) is a specific type of cognitive-behavioral psychotherapy developed in the late 1980s by psychologist Marsha M. Linehan to help better treat borderline personality disorder. Since its development, it has also been used for the treatment of other kinds of mental health disorders. The Oxford Handbook of DBT charts the development of DBT from its early inception to the current cutting edge state of knowledge about both the theoretical underpinnings of the treatment and its clinical application across a range of disorders and adaptations to new clinical groups. Experts in the treatment address the current state of the evidence with respect to the efficacy of the treatment, its effectiveness in routine clinical practice and central issues in the clinical and programmatic implementation of the treatment. In sum this volume provides a desk reference for clinicians and academics keen to understand the origins and current state of the science, and the art, of DBT.
As we know, rapid industrialization is a serious concern in the context of a healthy environment and public health due to the generation of huge volumes of toxic wastewater. Although various physico-chemical and biological approaches are available for the treatment of this wastewater, many of them are not effective. Now, there a number of emerging ecofriendly, cost-effective approaches utilizing microorganisms (bacterial/fungi/algae), green plants or their enzymes, and constructed wetland treatment systems in the treatment of wastewaters containing pollutants such as endocrine disrupting chemicals, toxic metals, pesticides, dyes, petroleum hydrocarbons and phenolic compounds. This book provides a much-needed, comprehensive overview of the various types of wastewater and their ecotoxicological effects on the environment, humans, animals and plants as well as various emerging and eco-friendly approaches for their treatment. It provides insights into the ecological problems and challenges in the treatment and management of wastewaters generated by various sources.
This contributed volume discusses the current status of the occurrences, fate and transport of persistent pollutants in water and wastewater. This contents compile the state-of-the-art of emerging technologies such as nanotechnology, advanced oxidation process, membrane processes, sorption, etc. for the clean-up of persistent pollutants in water including heavy metals, pharmaceuticals, phenolic compounds as well as microplastics and their by-products. This volume will be useful as a guide for the researchers to build strategies to deal with persistent pollutant. It also discusses the principal aspects of degradation mechanism of the pollutants, toxic by-products and effectiveness of the emerging technologies. This volume will be a useful guide for those working in soil and water protection, and environmental civil engineering.
Pedretti’s Occupational Therapy: Practice Skills for Physical Dysfunction, 8th Edition prepares you for occupational therapy practice with adults who have physical disabilities. This cornerstone text provides a foundation for the development of clinical reasoning skills in a comprehensive, case-based learning approach to physical dysfunction. New full color photos and helpful pedagogy, including threaded case studies, OT Practice Notes, ethical considerations, and end-of-chapter review questions, reinforce learning, enhance retention, and prompt you to apply principles in a clinical setting. UNIQUE! Threaded case studies, woven throughout each chapter, help you apply concepts to real-life clinical practice. UNIQUE! Ethical Considerations boxes highlight the key ethical concerns of treatment options so you can practice ethically. UNIQUE! OT Practice Notes convey important considerations for professional practice. Focuses on the occupational therapist’s role in health and wellness, which the OTA has identified as a key practice area in the 21st century. Information on prevention, rather than simply intervention or treatment, shows how OTs can take a proactive role in patient care. Evidence-based content included throughout, especially in regards to evaluation and intervention. Content on occupational therapy’s commitment to considering cultural and ethnic diversity in every chapter. Key terms, chapter outlines, chapter objectives lay out the information you can expect to learn from each chapter.