Analytical and Practical Aspects of Drug Testing in Hair

Analytical and Practical Aspects of Drug Testing in Hair

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  • Author: Pascal Kintz
  • Publisher: CRC Press
  • ISBN: 1420006193
  • Category : Law
  • Languages : en
  • Pages : 396

Many advances have been made since the publication of Drug Testing in Hair. The mid-1990s witnessed the progress in cannabis detection while the late 1990s focused on benzodiazepines detection and the applications in doping control. In more recent years, toxicologists centered on the detection in hair of a single exposure and the related applicatio


Hair Analysis in Clinical and Forensic Toxicology

Hair Analysis in Clinical and Forensic Toxicology

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  • Author: Pascal Kintz
  • Publisher: Academic Press
  • ISBN: 0128017104
  • Category : Science
  • Languages : en
  • Pages : 391

Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. - Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair - Demonstrates toxicological techniques relating to a variety of scenarios and exposure types - Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology - Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results


Hair in Toxicology

Hair in Toxicology

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  • Author: Desmond John Tobin
  • Publisher: Royal Society of Chemistry
  • ISBN: 184755251X
  • Category : Science
  • Languages : en
  • Pages : 377

Hair in Toxicology: An Important Biomonitor is the first book of its kind devoted exclusively to in-depth analysis of the hair shaft as an important tool for a diverse range of scientific investigations. This authoritative book combines contributions from experts in academic, governmental and industrial environments, to provide a unique, comprehensive look at: - Why hair can serve as an invaluable bio-resource in toxicology, with up-to-date reviews on hair growth, hair fibre formation and hair pigmentation - Information (including regulatory details) on the exposure of hair (and by extension the body) to drug and non-drug chemicals and pollutants - Toxicological issues relevant to the use of hair products (including colourants, shampoos and depilatories) - The ability of hair to capture information on personal identity, chemical exposure, and environmental interactions - How hair can provide an understanding of human life from archaeological and historical perspectives - Future direction in the use of hair in toxicology Hair in Toxicology: An Important Biomonitor is ideal as a reference and guide to investigations in the biomedical, biochemical and pharmaceutical sciences at the graduate and post graduate level.


Aging Hair

Aging Hair

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  • Author: Ralph M. Trüeb
  • Publisher: Springer Science & Business Media
  • ISBN: 3642026362
  • Category : Medical
  • Languages : en
  • Pages : 273

“Aged? But he does not appear aged, just look, his hair has remained young!” Marcel Proust, In Search of Lost Time (1913–27) The appearance of hair plays an important role in peoples’ overall physical appe- ance and self-perception. With today’s increasing life-expectation, the desire to look youthful plays a bigger role than ever. The hair care industry has become aware of this, and capable to deliver active products that are directed toward meeting this c- sumer demand. The discovery of pharmacological targets and the development of safe and effective drugs such as minoxidil and fnasteride also indicate strategies of the drug industry for maintenance of healthy and beautiful hair in the young and old. The study of hair aging focuses on two main streams of interest: On the one hand, the esthetic problem of aging hair and its management, in other words everything that happens outside the skin; on the other hand, the biological problem of aging hair, in terms of microscopic, biochemical, and molecular changes, in other words the “secret life” of the hair follicle in the depth of the skin. Hair aging comprises hair shaft aging, and aging of the hair follicle. The former involves weathering and photoaging of the hair shaft, while the latter manifests as decrease of melanocyte function (graying) and decrease in hair production (alopecia).


Operator Drug- and Alcohol-testing Across Modes

Operator Drug- and Alcohol-testing Across Modes

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  • Author: Dary D. Fiorentino
  • Publisher: Transportation Research Board
  • ISBN: 030922344X
  • Category : Business & Economics
  • Languages : en
  • Pages : 59

TRB Commercial Truck and Bus Safety Synthesis Program (CTBSSP) Synthesis 23: Operator Drug and Alcohol Testing Across Modes explores practices used to deter drug and alcohol use among operators within the U.S. Department of Transportation (DOT) regulated community. The report includes a brief history of the transportation workplace drug and alcohol testing program, the general approach, the reasons for testing, some of the issues that impact the validity of the tests, and an outline of the specific regulations by mode. Some alcohol and drug testing statistics are presented in the report to help provide a sense of the scope of the program and of the prevalence of illegal alcohol and drug use among safety sensitive employees. The report also highlights alternative strategies aimed at helping to deter illegal alcohol and drug use among employees.


Forensic Toxicology

Forensic Toxicology

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  • Author: Susannah Davies
  • Publisher: Royal Society of Chemistry
  • ISBN: 1788018109
  • Category : Medical
  • Languages : en
  • Pages : 590

New designer drugs, access to databases, and changing availability of samples for analysis have changed the face of modern forensic toxicology in recent years. Forensic Toxicology: Drug Use and Misuse brings together the latest information direct from experts in each sub-field of the discipline providing a broad overview of current thinking and the most innovative approaches to case studies. The text begins with an in-depth discussion of pharmaco­epidemiology, including information on the value of nationwide databases in forensic toxicology. The use and abuse of drugs in driving, sport and the workplace are then discussed by industry experts who are conducting case work in their field. Not only are new drug groups discussed (NPS), but also their constantly changing impact on drug legislation. Synthetic cannabinoids, khat and mephodrone are discussed in detail. Following a section devoted to legislation and defence, readers will find comprehensive chapters covering sample choice reflecting the increasing use of hair and oral fluid, and also the less commonly used sweat and nail analysis. New and old case examples are compared and contrasted in the final part of the book, which will enable readers to understand how drugs impact on each other and how the interpretative outcome of a case are dependent on many aspects. From use of pharmaceutical drugs in a clinical setting, through smart drugs to new psychoactive drugs, this book documents the wide range in which drugs today are abused. This book will be an essential resource for postgraduate students in forensic toxicology, and for researchers in forensic toxicology laboratories who need the latest data and knowledge.


Handbook of Drug Monitoring Methods

Handbook of Drug Monitoring Methods

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  • Author: Amitava Dasgupta
  • Publisher: Springer Science & Business Media
  • ISBN: 1588297802
  • Category : Medical
  • Languages : en
  • Pages : 441

Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.


The American Psychiatric Publishing Textbook of Substance Abuse Treatment

The American Psychiatric Publishing Textbook of Substance Abuse Treatment

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  • Author: Marc Galanter
  • Publisher: American Psychiatric Pub
  • ISBN: 1585625183
  • Category : Medical
  • Languages : en
  • Pages : 982

No other text available today offers what The American Psychiatric Publishing Textbook of Substance Abuse Treatment can: completely updated treatment information on a broad range of substance use disorders that is consistent with the new DSM-5 classification and thus reflective of how psychiatry is practiced today. Designed for researchers and mental health professionals ranging from trainee to licensed practitioner, the book is also appropriate for a diverse array of rehabilitation settings, from inpatient to community-based treatment. Full coverage is provided on 12-step programs, as well, including the latest outcomes research. Much of the material is new to this edition: A chapter has been added on science in the treatment of substance abuse, in which the authors discuss the history of scientific intervention in substance abuse and explore what happens to the brain when addicting drugs are consumed, review animal models and imaging techniques, and discuss current progress in the science of addiction. Chapters have been added on screening and brief intervention, reflecting the development of brief screening tools and research on the efficacy of interventions, and the role of "recovery" in chronic care disease management -- specifically what the treatment models for alcohol dependence and for diabetes can effectively borrow from each other. A new chapter focuses on the treatment of alcohol intoxication and withdrawal -- the first steps in treatment of alcohol use disorder. Two chapters on marijuana -- one on the neurobiology and one addressing treatment have been added. Given the accelerating trend toward decriminalization and legalization of this substance, clinicians will find this information of increasing importance. The section on substance use issues among gay men and lesbians has been expanded to include bisexual and transgender people in recognition of increased diversity among the population. Well-structured, with topics that follow logically and many practical, treatment-oriented features, such as quick reference tables and lists of recommended readings, The American Psychiatric Publishing Textbook of Substance Abuse Treatment is a classic that will enhance the education and practice of clinicians.


Information Resources in Toxicology, Volume 1: Background, Resources, and Tools

Information Resources in Toxicology, Volume 1: Background, Resources, and Tools

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  • Author:
  • Publisher: Academic Press
  • ISBN: 0128137258
  • Category : Technology & Engineering
  • Languages : en
  • Pages : 1055

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field


Information Resources in Toxicology

Information Resources in Toxicology

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  • Author: P.J. Bert Hakkinen
  • Publisher: Academic Press
  • ISBN: 0080920039
  • Category : Science
  • Languages : en
  • Pages : 1553

This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools and links to Web sites. IRT-IV is highly structured, providing easy access to its information. Among the "hot topics covered are Disaster Preparedness and Management, Nanotechnology, Omics, the Precautionary Principle, Risk Assessment, and Biological, Chemical and Radioactive Terrorism and Warfare are among the designated. - International in scope, with contributions from over 30 countries - Numerous key references and relevant Web links - Concise narratives about toxicologic sub-disciplines - Valuable appendices such as the IUPAC Glossary of Terms in Toxicology - Authored by experts in their respective sub-disciplines within toxicology