Making Genes, Making Waves

Making Genes, Making Waves

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  • Author: Jon Beckwith
  • Publisher: Harvard University Press
  • ISBN: 0674020677
  • Category : Biography & Autobiography
  • Languages : en
  • Pages : 251

In 1969, Jon Beckwith and his colleagues succeeded in isolating a gene from the chromosome of a living organism. Announcing this startling achievement at a press conference, Beckwith took the opportunity to issue a public warning about the dangers of genetic engineering. Jon Beckwith's book, the story of a scientific life on the front line, traces one remarkable man's dual commitment to scientific research and social responsibility over the course of a career spanning most of the postwar history of genetics and molecular biology. A thoroughly engrossing memoir that recounts Beckwith's halting steps toward scientific triumphs--among them, the discovery of the genetic element that turns genes on--as well as his emergence as a world-class political activist, Making Genes, Making Waves is also a compelling history of the major controversies in genetics over the last thirty years. Presenting the science in easily understandable terms, Beckwith describes the dramatic changes that transformed biology between the late 1950s and our day, the growth of the radical science movement in the 1970s, and the personalities involved throughout. He brings to light the differing styles of scientists as well as the different ways in which science is presented within the scientific community and to the public at large. Ranging from the travails of Robert Oppenheimer and the atomic bomb to the Human Genome Project and recent "Science Wars," Beckwith's book provides a sweeping view of science and its social context in the latter half of the twentieth century.


Making Waves

Making Waves

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  • Author: Roger Lewin
  • Publisher: Rodale Books
  • ISBN: 1623362407
  • Category : Biography & Autobiography
  • Languages : en
  • Pages : 240

The biography of a medical maverick who is challenging scientific convention with his astounding approach to achieving and maintaining health. Dr. Irving Dardik's radical notions about how all matter moves in interconnected waves has drawn deep skepticism from physicists, and his early attempts to put his theory into practice in the field of health care got him banned from practicing medicine in the 1990s. But now, after a decade's worth of rigorous research that seems to support Dardik's SuperWave theory, scientists at such esteemed institutions as MIT, Harvard, and Stanford Research International are signing on with Dardik's team to probe the possibilities. For example, Dardik's unique approach to physical exercise, based on his Principle, has achieved some remarkable successes in reversing symptoms of chronic disease. Making Waves weaves together two fascinating stories: Dardik's personal progression from vascular surgeon to scientific iconoclast and pioneer, chronicling his struggle to convince the scientific community to take him seriously; and the evolution of his mind-expanding SuperWave Principle. Colleagues--skeptics as well as supporters--consider the impact of SuperWave theory on current thinking about nature on all scales, from the universe to the subatomic world, and in the realms of biology, applied science, and medicine. The resulting read will interest those concerned with their own health and vitality as well as those curious about the fundamental workings of nature.


Blueprint, with a new afterword

Blueprint, with a new afterword

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  • Author: Robert Plomin
  • Publisher: MIT Press
  • ISBN: 0262357763
  • Category : Science
  • Languages : en
  • Pages : 296

A top behavioral geneticist makes the case that DNA inherited from our parents at the moment of conception can predict our psychological strengths and weaknesses. In Blueprint, behavioral geneticist Robert Plomin describes how the DNA revolution has made DNA personal by giving us the power to predict our psychological strengths and weaknesses from birth. A century of genetic research shows that DNA differences inherited from our parents are the consistent lifelong sources of our psychological individuality—the blueprint that makes us who we are. Plomin reports that genetics explains more about the psychological differences among people than all other factors combined. Nature, not nurture, is what makes us who we are. Plomin explores the implications of these findings, drawing some provocative conclusions—among them that parenting styles don't really affect children's outcomes once genetics is taken into effect. This book offers readers a unique insider's view of the exciting synergies that came from combining genetics and psychology. The paperback edition has a new afterword by the author.


Genes in Development

Genes in Development

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  • Author: Eva M. Neumann-Held
  • Publisher: Duke University Press
  • ISBN: 0822387336
  • Category : Science
  • Languages : en
  • Pages : 385

In light of scientific advances such as genomics, predictive diagnostics, genetically engineered agriculture, nuclear transfer cloning, and the manipulation of stem cells, the idea that genes carry predetermined molecular programs or blueprints is pervasive. Yet new scientific discoveries—such as rna transcripts of single genes that can lead to the production of different compounds from the same pieces of dna—challenge the concept of the gene alone as the dominant factor in biological development. Increasingly aware of the tension between certain empirical results and interpretations of those results based on the orthodox view of genetic determinism, a growing number of scientists urge a rethinking of what a gene is and how it works. In this collection, a group of internationally renowned scientists present some prominent alternative approaches to understanding the role of dna in the construction and function of biological organisms. Contributors discuss alternatives to the programmatic view of dna, including the developmental systems approach, methodical culturalism, the molecular process concept of the gene, the hermeneutic theory of description, and process structuralist biology. None of the approaches cast doubt on the notion that dna is tremendously important to biological life on earth; rather, contributors examine different ideas of how dna should be represented, evaluated, and explained. Just as ideas about genetic codes have reached far beyond the realm of science, the reconceptualizations of genetic theory in this volume have broad implications for ethics, philosophy, and the social sciences. Contributors. Thomas Bürglin, Brian C. Goodwin, James Griesemer, Paul Griffiths, Jesper Hoffmeyer, Evelyn Fox Keller, Gerd B. Müller, Eva M. Neumann-Held, Stuart A. Newman, Susan Oyama, Christoph Rehmann-Sutter, Sahotra Sarkar, Jackie Leach Scully, Gerry Webster, Ulrich Wolf


Making Waves

Making Waves

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  • Author: Roger Lewin
  • Publisher: Rodale
  • ISBN: 9781594860447
  • Category : Science
  • Languages : en
  • Pages : 258

A portrait of maverick scientist and iconoclastic medical researcher Irving Dardik describes his theory that all matter moves in interconnected waves and its implications in terms of the fields of health care, biology, medicine, and applied science. 35,000 first printing.


Your Genes, Your Choices

Your Genes, Your Choices

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  • Author: Catherine Baker
  • Publisher:
  • ISBN: 9780871686367
  • Category : DNA.
  • Languages : en
  • Pages : 96

Program discusses the Human Genome Project, the science behind it, and the ethical, legal and social issues raised by the project.


CRISPR People

CRISPR People

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  • Author: Henry T. Greely
  • Publisher: MIT Press
  • ISBN: 0262543885
  • Category : Technology & Engineering
  • Languages : en
  • Pages : 395

What does the birth of babies whose embryos had gone through genome editing mean--for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed.


The Code Breaker

The Code Breaker

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  • Author: Walter Isaacson
  • Publisher: Simon and Schuster
  • ISBN: 1982115874
  • Category : Biography & Autobiography
  • Languages : en
  • Pages : 560

A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.


Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

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  • Author: Robert T. Gerlai
  • Publisher: Academic Press
  • ISBN: 0128041161
  • Category : Mathematics
  • Languages : en
  • Pages : 710

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts


As Gods

As Gods

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  • Author: Matthew Cobb
  • Publisher: Basic Books
  • ISBN: 1541602846
  • Category : Science
  • Languages : en
  • Pages : 502

The thrilling and terrifying history of genetic engineering In 2018, scientists manipulated the DNA of human babies for the first time. As biologist and historian Matthew Cobb shows in As Gods, this achievement was one many scientists have feared from the start of the genetic age. Four times in the last fifty years, geneticists, frightened by their own technology, have called a temporary halt to their experiments. They ought to be frightened: Now we have powers that can target the extinction of pests, change our own genes, or create dangerous new versions of diseases in an attempt to prevent future pandemics. Both awe-inspiring and chilling, As Gods traces the history of genetic engineering, showing that this revolutionary technology is far too important to be left to the scientists. They have the power to change life itself, but should we trust them to keep their ingenuity from producing a hellish reality?