PDF Theoretical Aspects of Pedigree Analysis Download
- Author: Emil Ginsburg
- Publisher: RAMOT-TEL AVIV UNIVERSITY, ISRAEL
- ISBN: 9652744247
- Category : Biometric identification
- Languages : en
- Pages : 94
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Pedigree Analysis in R gives an introduction to the theory of relatedness and covers a range of applications in forensic and medical genetics. The book's material was developed through teaching courses on genetic relatedness, pedigree analysis and R, and offers insights from a decade of research activities in forensic and medical genetics. The R code in the book uses the ped suite, a unified collection of packages for pedigree analysis, developed by the author. All code examples are given in full, allowing accurate reproduction of figures and results. At the end of each chapter, a selection of exercises encourages the reader to explore further and perform their own analyses. Introduction to the theory of genetic relatedness, richly illustrated with classic and novel examples In-depth case studies including kinship testing, pedigree reconstruction, linkage analysis and clinical segregation analysis Easy-to-follow R code with explanations Based on the ped suite packages for pedigree analysis in R Suitable for R users at all levels, including complete beginners Exercises after each chapter
Quantitative Trait Loci (QTL) is a topic of major agricultural significance for efficient livestock production. This book covers various statistical methods that have been used or proposed for detection and analysis of QTL and marker-and gene-assisted selection in animal genetics and breeding.
This volume contains the selected contributed papers of the BIOMAT 2010 International Symposium which has been organized as a joint conference with the 2010 Annual Meeting of the Society for Mathematical Biology (www.smb.org) by invitation of the Director Board of this Society. The works presented at Tutorial and Plenary Sessions by expert keynote speakers have been also included.This book contains state-of-the-art articles on special research topics on mathematical biology, biological physics and mathematical modelling of biosystems; comprehensive reviews on interdisciplinary areas written by prominent leaders of scientific research groups. The treatment is both pedagogical and sufficiently advanced to enhance future scientific research.
This volume contains the selected contributed papers of the BIOMAT 2010 International Symposium which has been organized as a joint conference with the 2010 Annual Meeting of the Society for Mathematical Biology (http: //www.smb.org) by invitation of the Director Board of this Society. The works presented at Tutorial and Plenary Sessions by expert keynote speakers have been also included. This book contains state-of-the-art articles on special research topics on mathematical biology, biological physics and mathematical modelling of biosystems; comprehensive reviews on interdisciplinary areas written by prominent leaders of scientific research groups. The treatment is both pedagogical and sufficiently advanced to enhance future scientific research
Population Genetics and Microevolutionary Theory Explore the fundamentals of the biological implications of population genetic theory In the newly revised Second Edition of Population Genetics and Microevolutionary Theory, accomplished researcher and author Alan R. Templeton delivers a fulsome discussion of population genetics with coverage of exciting new developments in the field, including new discoveries in epigenetics and genome-wide studies. The book prepares students to successfully apply population genetics analytical tools by providing a solid foundation in microevolutionary theory. The book emphasizes that population structure forms the underlying template upon which quantitative genetics and natural selection operate and is a must-read for future population and evolutionary geneticists and those who wish to work in genetic epidemiology or conservation biology. You’ll learn about a wide array of topics, including quantitative genetics, the interactions of natural selection with other evolutionary forces, and selection in heterogeneous environments and age-structured populations. Appendices that cover genetic survey techniques and probability and statistics conclude the book. Readers will also benefit from the inclusion of: A thorough introduction to population genetics, including the scope of the subject, its premises, and the Hardy-Weinberg Model of Microevolution An exploration of systems of mating, including a treatment of the use of runs of homozygosity to show pedigree inbreeding in distant ancestors A practical discussion of genetic drift, including the use of effective sizes in conservation biology (with a discussion of African rhinos as an example) A concise examination of coalescence, including a treatment of the infinite sites model Perfect for graduate students in genetics and evolutionary biology programs and advanced undergraduate biology majors, Population Genetics and Microevolutionary Theory will also earn a place in the libraries of students taking courses in conservation biology, human genetics, bioinformatics, and genomics.
"EduGorilla's Biology Study Notes are the best-selling notes for CUET UG Section II : Biology Exam. Their content is well-researched and covers all topics related to Biology •The Study Guide are designed to help students prepare thoroughly for their exams, with topic-wise notes that are comprehensive and easy to understand. •The notes also include solved multiple-choice questions (MCQs) for self-evaluation, allowing students to gauge their progress and identify areas that require further improvement. •This Study Materials are perfect for understanding the pattern and type of questions asked in CUET UG. •This study notes are tailored to the latest syllabus as given by NTA for the exams, making them a valuable resource for exam preparation."
This volume presents an overview of current accomplishments and future directions in ecological theory. The twenty-three chapters cover a broad range of important topics, from the physiology and behavior of individuals or groups of organisms, through population dynamics and community structure, to the ecology of ecosystems and the geochemical cycles of the entire biosphere. The authors focus on ways in which theory, whether expressed mathematically or verbally, can contribute to defining and solving fundamental problems in ecology. A second aim is to highlight areas where dialogue between theorists and empiricists is likely to be especially rewarding. The authors are R. M. Anderson, C. W. Clark, M. L. Cody, J. E. Cohen, P. R. Ehrlich, M. W. Feldman, M. E. Gilpin, L. J. Gross, M. P. Hassell, H. S. Horn, P. Kareiva, M.A.R. Koehl, S. A. Levin, R. M. May, L. D. Mueller, R. V. O'Neill, S. W. Pacala, S. L. Pimm, T. M. Powell, H. R. Pulliam, J. Roughgarden, W. H. Schlesinger, H. H. Shugart, S. M. Stanley, J. H. Steele, D. Tilman, J. Travis, and D. L. Urban. Originally published in 1989. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
There are still many unknowns in the breeding of Thoroughbreds, but the international research coalition known as the Equine Genome Project is facilitating many new exciting discoveries. Dr. Matthew Binns is a leader of the project, an enterprise set up to map the equine genome, and with racing historian and bloodstock authority Tony Morris has written this important book on the theory, practice, art and science of Thoroughbred breeding. This long-awaited book describes how man came to express pedigree and to develop theories about it, and how practical breeders behaved in the light of their understanding. IT explains why many theories--including some still widely granted credibility today--are fallacious, examines the very real progress in knowledge since the principles of genetics were discovered, and focuses on the exciting developments of the last few years, when eminent geneticists have applied their expertise to the subject of the Thoroughbred. It has been the authors' endeavor to present the information in a form that may be readily understood by anyone who shares a love of the Thoroughbred and a fascination with what makes him what he is. Packed with absorbing history and cutting-edge science, this is a fascinating and illuminating book.
This balanced and well-integrated text gives a lucid overview of the entire process of genetic epidemiology, from familial aggregation through segregation, likage, and association studies. It is illustrated throughout with examples from the literature on cancer genetics. Statistical concepts are developed in depth, but with a focus on applications. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics are included. Oriented to graduate students in biostatistics, epidemiology, and human genetics, the book will also be a useful reference for researchers. It gives equal emphasis to study designs and data analysis.