Next-Generation Sequencing Data Analysis

2016-04-06
Next-Generation Sequencing Data Analysis

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  • Author: Xinkun Wang
  • Publisher: CRC Press
  • ISBN: 1482217899
  • Category : Mathematics
  • Languages : en
  • Pages : 252

A Practical Guide to the Highly Dynamic Area of Massively Parallel SequencingThe development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and phenotypic changes are connected to DNA mutation, polymorphi

Sequencing

1996-05
Sequencing

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  • Author: Arlene Cardozo
  • Publisher:
  • ISBN: 9780965123808
  • Category : Family & Relationships
  • Languages : en
  • Pages : 370

Next-generation DNA Sequencing Informatics

2015
Next-generation DNA Sequencing Informatics

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  • Author: Stuart M. Brown
  • Publisher:
  • ISBN: 9781621821236
  • Category : MEDICAL
  • Languages : en
  • Pages : 0

"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"

Bioinformatics for High Throughput Sequencing

2011-10-26
Bioinformatics for High Throughput Sequencing

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  • Author: Naiara Rodríguez-Ezpeleta
  • Publisher: Springer Science & Business Media
  • ISBN: 1461407826
  • Category : Science
  • Languages : en
  • Pages : 258

Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. The generation of gigabases of sequence information for each of this huge bandwidth of applications in just a few days makes the development of bioinformatics applications for next generation sequencing data analysis as urgent as challenging.

Next-Generation Genome Sequencing

2011-08-24
Next-Generation Genome Sequencing

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  • Author: Michal Janitz
  • Publisher: John Wiley & Sons
  • ISBN: 3527644733
  • Category : Science
  • Languages : en
  • Pages : 281

Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug discovery and health care. As such, it presents a detailed comparative analysis of commercially available platforms as well as insights into alternative, emerging sequencing techniques. In addition, the book not only covers the principles of DNA sequencing techniques but also social, ethical and commercial aspects, the concept of personalized medicine and a five-year perspective of DNA sequencing.

Mapping and Sequencing the Human Genome

1988-01-01
Mapping and Sequencing the Human Genome

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  • Author: National Research Council
  • Publisher: National Academies Press
  • ISBN: 0309038405
  • Category : Science
  • Languages : en
  • Pages : 128

There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Nanopore Sequencing: An Introduction

2019-04-05
Nanopore Sequencing: An Introduction

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  • Author: Daniel Branton
  • Publisher: World Scientific
  • ISBN: 9813270624
  • Category : Science
  • Languages : en
  • Pages : 217

This is an introductory text and laboratory manual to be used primarily in undergraduate courses. It is also useful for graduate students and research scientists who require an introduction to the theory and methods of nanopore sequencing. The book has clear explanations of the principles of this emerging technology, together with instructional material written by experts that describes how to use a MinION nanopore instrument for sequencing in research or the classroom.At Harvard University the book serves as a textbook and lab manual for a university laboratory course designed to intensify the intellectual experience of incoming undergraduates while exploring biology as a field of concentration. Nanopore sequencing is an ideal topic as a path to encourage students about the range of courses they will take in Biology by pre-emptively addressing the complaint about having to take a course in Physics or Maths while majoring in Biology. The book addresses this complaint by concretely demonstrating the range of topics — from electricity to biochemistry, protein structure, molecular engineering, and informatics — that a student will have to master in subsequent courses if he or she is to become a scientist who truly understands what his or her biology instrument is measuring when investigating biological phenomena.

Sequencing

2010-04
Sequencing

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  • Author: Michael Metzger
  • Publisher:
  • ISBN: 9780982656600
  • Category : Business & Economics
  • Languages : en
  • Pages : 216

Watson and Crick discovered the human DNA. What made the difference was deciphering it. Like the human body, every organization has a DNA. What will make the difference is not seeing it, but sequencing it. It's the key to long-term success at innovation. Sequencing, written by business consultant Michael Metzger, explores what is required for a company to develop a culture that promotes innovation for the long haul. Harvard's Clayton Christensen reports that few companies have the capacity to innovate. The more success a company achieves, the harder it is for the company to innovate. And yet the reality is that companies innovate or die. Metzger outlines the steps necessary to sustain innovation - the culture, conscience, and C-level leadership required. It begins by having an accurate assessment of human nature and reality. Institutional leaders ignore this book at their peril.

Yoga Sequencing

2012-09-18
Yoga Sequencing

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  • Author: Mark Stephens
  • Publisher: North Atlantic Books
  • ISBN: 1583944974
  • Category : Health & Fitness
  • Languages : en
  • Pages : 529

The yoga teacher’s guide to planning and sequencing yoga classes—with over 2,000 instructional photos and 67 yoga pose sequences for students of all skill levels. Also features additional resources, including yoga class planning worksheets, comprehensive glossaries, and much more! Addressing one of the most popular topics in the yoga profession, this book offers 67 model sequences of yoga poses (asanas) that cover the broad range of yoga student experience. Inside, established and aspiring yoga teachers will find: • Over 2,000 instructional photos and guide to over 150 yoga asanas • Multiple sequences for beginning, intermediate, and advanced students • Yoga sequences for kids, teens, seniors, and women across their life cycle • Yoga classes designed for relieving depression and anxiety • Sequences for each of the major chakras and ayurvedic constitutions • Guidance for teaching breathing (pranayama) and meditation techniques • Glossary of terms and alphabetical asana index with thumbnail photographs • Yoga class planning worksheets • Representative sequences from several popular styles of hatha yoga • And many more resources for further reading! Drawing on ancient yoga philosophy and contemporary insights into functional anatomy, biomechanics, and kinesiology, Yoga Sequencing is the ultimate guide teachers looking to bring the transformative power of yoga into their practice and classes.

Clinical Applications for Next-Generation Sequencing

2015-09-10
Clinical Applications for Next-Generation Sequencing

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  • Author: Urszula Demkow
  • Publisher: Academic Press
  • ISBN: 0128018410
  • Category : Science
  • Languages : en
  • Pages : 336

Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments. Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients. The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia. - Fills the gap between state-of-the-art technology and evidence-based practice - Provides an educational opportunity which advances patient care through the transfer of NGS to real-world patient assessment - Promotes a practical tool that clinicians can apply directly to patient care - Includes a systematic framework for understanding the role of NGS testing in many common and rare diseases - Presents evidence regarding the important role of NGS in current diagnostic strategies