This book constitutes the refereed proceedings of the First International Conference on Affective Computing and Intelligent Interaction, ACII 2005, held in Beijing, China in October 2005 as an associated event of ICCV 2005, the International Conference on Computer Vision. The 45 revised full papers and 81 revised poster papers presented were carefully reviewed and selected from 198 submissions. They cover a wide range of topics, such as facial expression recognition, face animation, emotional speech synthesis, intelligent agent, and virtual reality. The papers are organized in topical sections on affective face and gesture processing, affective speech processing, evaluation of affective expressivity, affective database, annotation and tools, psychology and cognition of affect, and affective interaction and systems and applications.