Decellularized Materials

2021-04-28
Decellularized Materials

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  • Author: Xiaoming Li
  • Publisher: Springer Nature
  • ISBN: 9813369620
  • Category : Medical
  • Languages : en
  • Pages : 517

This book will consist of 8 chapters, in which important issues regarding decellularized materials (DMs) will be discussed. This book will provide special knowledge of materials for the persons with biomedical background, and special biomedical knowledge for the persons with the background of materials, which will hopefully become a valuable informative read for the researchers and students of biomedical engineering major.

Decellularized Extracellular Matrix

2019-12-05
Decellularized Extracellular Matrix

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  • Author: Takashi Hoshiba
  • Publisher: Royal Society of Chemistry
  • ISBN: 1788014677
  • Category : Science
  • Languages : en
  • Pages : 368

Using this book, the reader will gain a good foundation to the field complemented with a broad overview of characterisation, microfabrication and applications.

Musculoskeletal Tissue Regeneration

2008-04-11
Musculoskeletal Tissue Regeneration

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  • Author: William S. Pietrzak
  • Publisher: Springer Science & Business Media
  • ISBN: 1597452394
  • Category : Medical
  • Languages : en
  • Pages : 649

The repair of musculoskeletal tissue is a vital concern of all surgical specialties, orthopedics and related disciplines. Written by recognized experts, this book aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena. A valuable resource for researchers, developers, and clinicians, the book presents a foundation to propel the technology and integration of the current state of knowledge into the 21st century.

Decellularized Scaffolds and Organogenesis

2018-07-21
Decellularized Scaffolds and Organogenesis

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  • Author: Kursad Turksen
  • Publisher: Humana Press
  • ISBN: 9781493976553
  • Category : Science
  • Languages : en
  • Pages :

This practical, hands-on volume examines the use of decellularized tissues and organs as biologically-active scaffolds by providing numerous approaches from experts in the field. While knowledge of how to grow and differentiate cells in culture has dramatically improved over time, the book addresses the challenges of how to instruct particular cells of interest to recognize and respond to their environment so as to proliferate, differentiate, and function for restoration of original tissue and organ form and function. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Decellularized Scaffolds and Organogenesis: Methods and Protocols share novel approaches and insights that will provide new opportunities for those already in the field or moving to enter the field.

Stem Cell and Tissue Engineering

2011
Stem Cell and Tissue Engineering

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  • Author: Song Li
  • Publisher: World Scientific
  • ISBN: 9814317055
  • Category : Science
  • Languages : en
  • Pages : 473

Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.

Smart Biomaterials

2014-05-28
Smart Biomaterials

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  • Author: Mitsuhiro Ebara
  • Publisher: Springer
  • ISBN: 4431544003
  • Category : Technology & Engineering
  • Languages : en
  • Pages : 380

This book provides comprehensive coverage of smart biomaterials and their potential applications, a field that is developing at a very rapid pace. Because smart biomaterials are an emerging class of biomaterials that respond to small changes in external stimuli with large discontinuous changes in their physical properties, they have been designed to act as an “on–off” switch for, among others, bio separation, immunoanalysis, drug delivery technologies, gene therapy, diagnostics, bio sensors and artificial muscles. After an introduction to the topic and the history of smart biomaterials, the author gives the reader an in-depth look at the properties, mechanics, and characterization of smart biomaterials including hydrogels, particles, assemblies, surfaces, fibers and conjugates. Information on the wide range of applications for these materials follows, including drug delivery, tissue engineering, diagnostics, biosensors, bio separation and actuators. In addition, recent advances in shape memory biomaterials as active components of medical devices are also presented.

Biofabrication and 3D Tissue Modeling

2019-01-02
Biofabrication and 3D Tissue Modeling

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  • Author: Dong-Woo Cho
  • Publisher: Royal Society of Chemistry
  • ISBN: 1788011988
  • Category : Technology & Engineering
  • Languages : en
  • Pages : 369

3D tissue modelling is an emerging field used for the investigation of disease mechanisms and drug development. The two key drivers of this upsurge in research lie in its potential to offer a way to reduce animal testing with respect to biotoxicity analysis, preferably on physiology recapitulated human tissues and, additionally, it provides an alternative approach to regenerative medicine. Integrating physics, chemistry, materials science, and stem cell and biomedical engineering, this book provides a complete foundation to this exciting, and interdisciplinary field. Beginning with the basic principles of 3D tissue modelling, the reader will find expert reviews on key fabrication technologies and processes, including microfluidics, microfabrication technology such as 3D bioprinting, and programming approaches to emulating human tissue complexity. The next stage introduces the reader to a range of materials used for 3D tissue modelling, from synthetic to natural materials, as well as the emerging field of tissue derived decellularized extracellular matrix (dECM). A whole host of critical applications are covered, with several chapters dedicated to hard and soft tissues, as well as focused reviews on the respiratory and central nervous system. Finally, the development of in vitro tissue models to screen drugs and study progression and etiologies of diseases, with particular attention paid to cancer, can be found.

Scaffolds for Tissue Engineering

2014-06-10
Scaffolds for Tissue Engineering

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  • Author: Claudio Migliaresi
  • Publisher: CRC Press
  • ISBN: 9814463213
  • Category : Medical
  • Languages : en
  • Pages : 698

Scaffolds for tissue engineering are devices that exploit specific and complex physical and biological functions, in vitro or in vivo, and communicate through biochemical and physical signals with cells and, when implanted, with the body environment. Scaffolds are produced mainly with synthetic materials, and their fabrication technologies are derived from already well-established industrial processes, with some new specific technologies having been developed in the last years to address required complexities. Often, a generalist approach is followed for the translation of materials and technologies designed for other applications, without considering the specific role of scaffolds from a physical and biological point of view. The book illustrates scaffold design principles, with particular relevance to the biological requirements needed to control and drive the biological cross talk, and reviews materials and fabrication and validation methods.

Biomaterials Nanoarchitectonics

2016-02-11
Biomaterials Nanoarchitectonics

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  • Author: Mitsuhiro Ebara
  • Publisher: William Andrew
  • ISBN: 0323374999
  • Category : Technology & Engineering
  • Languages : en
  • Pages : 362

Biomaterials Nanoarchitectonics, written from the perspectives of authors form NIMS and other researchers worldwide, provides readers with an explanation of the theory and techniques of nanoarchitectonics, exploring its applications in biomedical fields, including regenerative medicine, drug delivery, and diagnostic and treatment systems based on pathogenic mechanisms. The book also explains the use of nanomaterials that enable 'materials therapy', in which the materials themselves elicit a sustainable, curative effect from living tissue. Authored by the team that coined the term nanoarchitectonics, who explain their approach to the design of smart/functional nanomaterials and their applications in the biomedical arena Explores how materials designed and produced with nanoarchitectonics methods can be used to enhance the natural regenerative power of the human body Enables scientists and researchers to gain a deeper understanding of the specific challenges of materials design at the nanoscale

Decellularized Extracellular Matrix

2019-12-05
Decellularized Extracellular Matrix

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  • Author: Tetsuji Yamaoka
  • Publisher: Royal Society of Chemistry
  • ISBN: 1839161264
  • Category : Technology & Engineering
  • Languages : en
  • Pages : 368

The extracellular matrix (ECM) supports cells and regulates various cellular functions in our body. The native ECM promises to provide an excellent scaffold for regenerative medicine. In order to use the ECM as a scaffold in medicine, its cellular fractions need to be removed while retaining its structural and compositional properties. This process is called decellularization, and the resulting product is known as the decellularized extracellular matrix (dECM). This book focuses on the sources of dECM and its preparation, characterization techniques, fabrication, and applications in regenerative medicine and biological studies. Using this book, the reader will gain a good foundation in the field of ECM decellularization complemented with a broad overview of dECM characterization, ranging from structural observation and compositional assessment to immune responses against dECM and applications, ranging from microfabrication and 3D-printing to the application of tissue-derived dECM in vascular grafts and corneal tissue engineering etc. The book closes with a section dedicated to cultured cell dECM, a complementary technique of tissue-derived dECM preparation, for application in tissue engineering and regenerative medicine, addressing its use in stem cell differentiation and how it can help in the study of the tumor microenvironment as well as in clinical trials of peripheral nerve regeneration.