Current Medicinal Chemistry

Current Medicinal Chemistry

PDF Current Medicinal Chemistry Download

  • Author:
  • Publisher:
  • ISBN:
  • Category :
  • Languages : en
  • Pages : 96


Current Medicinal Chemistry

Current Medicinal Chemistry

PDF Current Medicinal Chemistry Download

  • Author:
  • Publisher:
  • ISBN:
  • Category :
  • Languages : en
  • Pages : 100


Recent Advances in Medicinal Chemistry

Recent Advances in Medicinal Chemistry

PDF Recent Advances in Medicinal Chemistry Download

  • Author: Atta-ur-Rahman
  • Publisher: Elsevier
  • ISBN: 0128039620
  • Category : Science
  • Languages : en
  • Pages : 486

Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more. Edited and written by leading experts in medicinal chemistry research Reviews recent advances in the field, including the characterization of inorganic nanomaterials as therapeutic vehicles Covers a variety of topical areas, such as HPLC and in the analysis of tricyclic antidepressants in biological samples, and tannins and their influence on health


HIV-1 Integrase

HIV-1 Integrase

PDF HIV-1 Integrase Download

  • Author: Nouri Neamati
  • Publisher: John Wiley & Sons
  • ISBN: 1118015363
  • Category : Science
  • Languages : en
  • Pages : 710

This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.


An Introduction to Medicinal Chemistry

An Introduction to Medicinal Chemistry

PDF An Introduction to Medicinal Chemistry Download

  • Author: Graham L. Patrick
  • Publisher: Oxford University Press
  • ISBN: 0199697396
  • Category : Medical
  • Languages : en
  • Pages : 814

This volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.


Comprehensive Medicinal Chemistry III

Comprehensive Medicinal Chemistry III

PDF Comprehensive Medicinal Chemistry III Download

  • Author:
  • Publisher: Elsevier
  • ISBN: 9780128032008
  • Category : Science
  • Languages : en
  • Pages : 0

Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs


Medicinal Chemistry with Pharmaceutical Product Development

Medicinal Chemistry with Pharmaceutical Product Development

PDF Medicinal Chemistry with Pharmaceutical Product Development Download

  • Author: Debarshi Kar Mahapatra
  • Publisher: CRC Press
  • ISBN: 0429947143
  • Category : Medical
  • Languages : en
  • Pages : 290

This volume focuses on novel therapeutics and strategies for the development of pharmaceutical products, keeping the drug molecule as the central component. It discusses current theoretical and practical aspects of pharmaceuticals for the discovery and development of novel therapeutics for health problems. Explaining the necessary features essential for pharmacological activity, it takes an interdisciplinary approach by including a unique combination of pharmacy, chemistry, and medicine along with clinical aspects. It takes into consideration the therapeutic regulations of the USP along with all the latest therapeutic guidelines put forward by WHO, and the US Food and Drug Administration.


Medicinal Chemistry

Medicinal Chemistry

PDF Medicinal Chemistry Download

  • Author: Norma K Dunlap
  • Publisher: Garland Science
  • ISBN: 1351586203
  • Category : Medical
  • Languages : en
  • Pages : 991

Medicinal Chemistry begins with the history of the field, starting from the serendipitous use of plant preparations to current practice of design- and target-based screening methods. Written from the perspective of practicing medicinal chemists, the text covers key drug discovery activities such as pharmacokinetics and patenting, as well as the classes and structures of drug targets (receptors, enzymes, nucleic acids, and protein-protein and lipid interactions) with numerous examples of drugs acting at each type. Selected therapeutic areas include drugs to treat cancer, infectious diseases, and central nervous system disorders. Throughout the book, historical and current examples illustrate the progress to market and case studies explore the applications of concepts discussed in the text. Each chapter features a Journal Club, as well as review and application questions to enhance and test comprehension. This textbook is ideal for upper-level undergraduates and graduate students taking a one-semester survey course on medicinal chemistry and/or drug discovery, as well as scientists entering the pharmaceutical industry.


Accounts in Drug Discovery

Accounts in Drug Discovery

PDF Accounts in Drug Discovery Download

  • Author: Joel Barrish
  • Publisher: Royal Society of Chemistry
  • ISBN: 1849731268
  • Category : Medical
  • Languages : en
  • Pages : 397

Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome. The Editors cover a wide range of therapeutic areas and medicinal chemistry strategies, including lead optimization starting from high-throughput screening "hits" as well as rational, structure-based design. The chapters include "follow-ons" and "next generation" compounds that aim to improve upon first-generation agents. This volume surveys the range of challenges commonly faced by medicinal chemistry researchers, including the optimization of metabolism and pharmacokinetics, toxicology, pharmaceutics and pharmacology, including proof-of-concept in the clinic for novel biological targets. The case studies include medicinal chemistry stories on recently approved and marketed drugs, but also chronicle "near-misses," i.e. exemplary compounds that may have proceeded well into the clinic but for various reasons did not result in a successful registration. As the vast majority of projects fail prior to registration, much can be learned from such narratives. By sharing a wide range of drug discovery experiences and information across the community of medicinal chemists in both industry and academia, the Editors believe that these accounts will provide insights into the art of medicinal chemistry as it is currently practiced and will help to serve the needs of active medicinal chemists.


Handbook of Research on Medicinal Chemistry

Handbook of Research on Medicinal Chemistry

PDF Handbook of Research on Medicinal Chemistry Download

  • Author: Debarshi Kar Mahapatra
  • Publisher: Taylor & Francis
  • ISBN: 135180023X
  • Category : Medical
  • Languages : en
  • Pages : 628

This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and nutraceuticals. The editors keep the drug molecule as the central component of the volume and aim to explain the associated features essential to exhibiting pharmacological activity. With a unique combination of chapters in biology, clinical aspects, biochemistry, synthetic chemistry, medicine and technology, the volume provides broad exposure to the essential aspect of pharmaceuticals. The volume many important aspects of medicinal chemistry, including techniques in drug discovery pharmacological aspects of natural products chemical mediators: druggable targets advances in medicinal chemistry The field of medicinal chemistry is growing at an unprecedented pace, and this volume takes an interdisciplinary approach, covering a range of new research and new practices in the field. The volume takes into account the latest therapeutic guidelines put forward by the World Health Organization and the U.S Food and Drug Administration.. Topics include: drug design drug discovery natural products and supplements and nutraceuticals pharmaceutical approaches to sexual dysfunction drug resistance parasites new natural compounds and identification of new targets stereochemistry aspects in medicinal chemistry common drug interactions in daily practices Handbook of Research on Medicinal Chemistry: Innovations and Methodologies will be a valuable addition to the bookshelves of pharmaceutical scientists and faculty as well as for industry professionals.