Down Syndrome: From Understanding the Neurobiology to Therapy

Down Syndrome: From Understanding the Neurobiology to Therapy

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  • Author:
  • Publisher: Elsevier
  • ISBN: 0444543007
  • Category : Medical
  • Languages : en
  • Pages : 273

Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system. This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes. It brings together scientists of diverse backgrounds, by facilitating the integration of research directed at different levels of biological organization, and by highlighting translational research and the application of the existing scientific knowledge to develop improved DS treatments and cures. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist


Babies with Down Syndrome

Babies with Down Syndrome

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  • Author: Susan J. Skallerup
  • Publisher: Special Needs Collection
  • ISBN: 9781890627553
  • Category : Children
  • Languages : en
  • Pages : 0

Babies with Down Syndrome-- the book that tens of thousands of new parents have turned to for information and guidance-- is now completely revised and updated. Covering medical care, daily care, family life, development, early interention, learning, legal rights, and much more, the new edition is a complete roadmap to every aspect of your child's health and well being from birth through age five.


Teaching the Infant with Down Syndrome

Teaching the Infant with Down Syndrome

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  • Author: Marci J. Hanson
  • Publisher: Pro-Ed
  • ISBN:
  • Category : Family & Relationships
  • Languages : en
  • Pages : 310


Medical & Surgical Care for Children with Down Syndrome

Medical & Surgical Care for Children with Down Syndrome

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  • Author: Don C. Van Dyke
  • Publisher:
  • ISBN:
  • Category : Family & Relationships
  • Languages : en
  • Pages : 436

This guide covers medical treatments and conditions-from heart disease to skin conditions-more common among children with Down syndrome.


Facts about Down Syndrome

Facts about Down Syndrome

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  • Author:
  • Publisher:
  • ISBN:
  • Category : Down syndrome
  • Languages : en
  • Pages : 20


Choosing Down Syndrome

Choosing Down Syndrome

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  • Author: Chris Kaposy
  • Publisher: MIT Press
  • ISBN: 0262546248
  • Category : Science
  • Languages : en
  • Pages : 237

An argument that more people should have children with Down syndrome, written from a pro-choice, disability-positive perspective. The rate at which parents choose to terminate a pregnancy when prenatal tests indicate that the fetus has Down syndrome is between 60 and 90 percent. In Choosing Down Syndrome, Chris Kaposy offers a carefully reasoned ethical argument in favor of choosing to have such a child. Arguing from a pro-choice, disability-positive perspective, Kaposy makes the case that there is a common social bias against cognitive disability that influences decisions about prenatal testing and terminating pregnancies, and that more people should resist this bias by having children with Down syndrome. Drawing on accounts by parents of children with Down syndrome, and arguing for their objectivity, Kaposy finds that these parents see themselves and their families as having benefitted from having a child with Down syndrome. To counter those who might characterize these accounts as based on self-deception or expressing adaptive preference, Kaposy cites supporting evidence, including divorce rates and observational studies showing that families including children with Down syndrome typically function well. Himself the father of a child with Down syndrome, Kaposy argues that cognitive disability associated with Down syndrome does not lead to diminished well-being. He argues further that parental expectations are influenced by neoliberal ideologies that unduly focus on the supposed diminished economic potential of a person with Down syndrome. Kaposy does not advocate restricting access to abortion or prenatal testing for Down syndrome, and he does not argue that it is ethically mandatory in all cases to give birth to a child with Down syndrome. People should be free to make important decisions based on their values. Kaposy's argument shows that it may be consistent with their values to welcome a child with Down syndrome into the family.


Helping Children with Down Syndrome Communicate Better

Helping Children with Down Syndrome Communicate Better

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  • Author: Libby Kumin
  • Publisher:
  • ISBN: 9781890627546
  • Category : Children
  • Languages : en
  • Pages : 0

Provides information and resources to improve children's communicaton at school, home and in the wider community.


Testing Women, Testing the Fetus

Testing Women, Testing the Fetus

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  • Author: Rayna Rapp
  • Publisher: Routledge
  • ISBN: 1135963924
  • Category : Social Science
  • Languages : en
  • Pages : 376

Rich with the voices and stories of participants, these touching, firsthand accounts examine how women of diverse racial, ethnic, class and religious backgrounds perceive prenatal testing, the most prevalent and routinized of the new reproducing technologies. Based on the author's decade of research and her own personal experiences with amniocentesis, Testing Women, Testing the Fetus explores the "geneticization" of family life in all its complexity and diversity.


Children with Down's Syndrome

Children with Down's Syndrome

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  • Author: Stephanie Lorenz
  • Publisher: Routledge
  • ISBN: 1136612416
  • Category : Education
  • Languages : en
  • Pages : 112

This practical handbook offers advice on strategies for meeting the special educational needs of children with Down's syndrome in mainstream schools. The aim is to increase the confidence of support assistants, teachers, SENCOs and senior managers in both primary and secondary schools in providing a quality education for these pupils, while using scarce resources to best effect. The author offers an introduction to the particular characteristics of children with Down's syndrome and their impact on learning and behaviour. She considers the benefits of inclusive education and the most effective ways in which the National Curriculum can be made accessible. She also examines working with the whole-school, parents and outside agencies, as well as providing practical resources such as photocopiable proformas and checklists, materials for INSET in schools and support services and a list of reading materials.


Gifts

Gifts

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  • Author: Kathryn Lynard Soper
  • Publisher: Special Needs Collection
  • ISBN: 9781606132760
  • Category : Children with disabilities
  • Languages : en
  • Pages : 0

This commemorative 10th anniversary edition of Gifts will include 10 new personal stories, along with "where are they now" updates on many of the children and families featured in the first edition. Gifts is the much-loved collection of over 60 essays written by mothers who share their truths about raising children with Down syndrome. Powerful then and powerful now, it affirms over and over that a life with an extra chromosome is one worth living.