Understanding Genetics

Understanding Genetics

PDF Understanding Genetics Download

  • Author: Genetic Alliance
  • Publisher: Lulu.com
  • ISBN: 0982162219
  • Category : Biology
  • Languages : en
  • Pages : 104

The purpose of this manual is to provide an educational genetics resource for individuals, families, and health professionals in the New York - Mid-Atlantic region and increase awareness of specialty care in genetics. The manual begins with a basic introduction to genetics concepts, followed by a description of the different types and applications of genetic tests. It also provides information about diagnosis of genetic disease, family history, newborn screening, and genetic counseling. Resources are included to assist in patient care, patient and professional education, and identification of specialty genetics services within the New York - Mid-Atlantic region. At the end of each section, a list of references is provided for additional information. Appendices can be copied for reference and offered to patients. These take-home resources are critical to helping both providers and patients understand some of the basic concepts and applications of genetics and genomics.


Understanding Genes

Understanding Genes

PDF Understanding Genes Download

  • Author: Kostas Kampourakis
  • Publisher: Cambridge University Press
  • ISBN: 1108858635
  • Category : Science
  • Languages : en
  • Pages : 241

What are genes? What do genes do? These questions are not simple and straightforward to answer; at the same time, simplistic answers are quite prevalent and are taken for granted. This book aims to explain the origin of the gene concept, its various meanings both within and outside science, as well as to debunk the intuitive view of the existence of 'genes for' characteristics and disease. Drawing on contemporary research in genetics and genomics, as well as on ideas from history of science, philosophy of science, psychology and science education, it explains what genes are and what they can and cannot do. By presenting complex concepts and research in a comprehensible and rigorous manner, it examines the potential impact of research in genetics and genomics and how important genes actually are for our lives. Understanding Genes is an accessible and engaging introduction to genes for any interested reader.


Genomics of Rare Diseases

Genomics of Rare Diseases

PDF Genomics of Rare Diseases Download

  • Author: Claudia Gonzaga-Jauregui
  • Publisher: Academic Press
  • ISBN: 0128204362
  • Category : Medical
  • Languages : en
  • Pages : 316

Genomics of Rare Diseases: Understanding Disease Genetics Using Genomic Approaches, a new volume in the Translational and Applied Genomics series, offers readers a broad understanding of current knowledge on rare diseases through a genomics lens. This clear understanding of the latest molecular and genomic technologies used to elucidate the molecular causes of more than 5,000 genetic disorders brings readers closer to unraveling many more that remain undefined and undiscovered. The challenges associated with performing rare disease research are also discussed, as well as the opportunities that the study of these disorders provides for improving our understanding of disease architecture and pathophysiology. Leading chapter authors in the field discuss approaches such as karyotyping and genomic sequencing for the better diagnosis and treatment of conditions including recessive diseases, dominant and X-linked disorders, de novo mutations, sporadic disorders and mosaicism. Compiles applied case studies and methodologies, enabling researchers, clinicians and healthcare providers to effectively classify DNA variants associated with disease and patient phenotypes Discusses the main challenges in studying the genetics of rare diseases through genomic approaches and possible or ongoing solutions Explores opportunities for novel therapeutics Features chapter contributions from leading researchers and clinicians


The Genetics of Health

The Genetics of Health

PDF The Genetics of Health Download

  • Author: Sharad P. Paul
  • Publisher: Simon and Schuster
  • ISBN: 1501155423
  • Category : Family & Relationships
  • Languages : en
  • Pages : 272

"SHARAD P. PAUL, MD, is starting a health RxEvolution. He argues it's time to stop relying on prescriptive drugs to alleviate all ailments and instead take charge of your own life wellness. He walks readers through the genes that are key to our physical and mental fitness and longevity, the genesis of those genes, and how actions play a role in the expression of genes in our bodies. Each chapter concludes with practical and easily implemented actions that help readers start managing their daily wellbeing and encourages them to personalize his steps for their own bodies and lifestyles. Dr. Paul has been recognized for his thought leadership, compassion, and entrepreneurialism. In addition to his busy skin surgery schedule, he offers 7,000 free skin cancer checks every year and even invented a skin graft technique that reduces costs and healing time for patients. With The Genetics of Health, he offers the knowledge and the guidance for readers to personally take charge of reducing their own healthcare costs and sick days, and to seize the healthiest life possible"--


The Epigenetics Revolution

The Epigenetics Revolution

PDF The Epigenetics Revolution Download

  • Author: Nessa Carey
  • Publisher: Columbia University Press
  • ISBN: 0231530714
  • Category : Science
  • Languages : en
  • Pages : 353

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.


The Gene

The Gene

PDF The Gene Download

  • Author: Siddhartha Mukherjee
  • Publisher: Simon and Schuster
  • ISBN: 1476733538
  • Category : Medical
  • Languages : en
  • Pages : 624

The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).


Computational Genetics and Genomics

Computational Genetics and Genomics

PDF Computational Genetics and Genomics Download

  • Author: Gary Peltz
  • Publisher: Springer Science & Business Media
  • ISBN: 1592599303
  • Category : Medical
  • Languages : en
  • Pages : 308

Ultimately, the quality of the tools available for genetic analysis and experimental disease models will be assessed on the basis of whether they provide new information that generates novel treatments for human disease. In addition, the time frame in which genetic discoveries impact clinical practice is also an important dimension of how society assesses the results of the significant public financial investment in genetic research. Because of the investment and the increased expectation that new tre- ments will be found for common diseases, allowing decades to pass before basic discoveries are made and translated into new therapies is no longer acceptable. Computational Genetics and Genomics: Tools for Understanding Disease provides an overview and assessment of currently available and developing tools for genetic analysis. It is hoped that these new tools can be used to identify the genetic basis for susceptibility to disease. Although this very broad topic is addressed in many other books and journal articles, Computational Genetics and Genomics: Tools for Understanding Disease focuses on methods used for analyzing mouse genetic models of biomedically - portant traits. This volume aims to demonstrate that commonly used inbred mouse strains can be used to model virtually all human disea- related traits. Importantly, recently developed computational tools will enable the genetic basis for differences in disease-related traits to be rapidly identified using these inbred mouse strains. On average, a decade is required to carry out the development process required to demonstrate that a new disease treatment is beneficial.


DNA and RNA

DNA and RNA

PDF DNA and RNA Download

  • Author: Linley Erin Hall
  • Publisher: The Rosen Publishing Group, Inc
  • ISBN: 1435895320
  • Category : Juvenile Nonfiction
  • Languages : en
  • Pages : 82

Introduces DNA and RNA, discussing how heredity works, what can happen when the code goes wrong, replication, and new advances in science and technology.


Medical Genetics at a Glance

Medical Genetics at a Glance

PDF Medical Genetics at a Glance Download

  • Author: Dorian J. Pritchard
  • Publisher: John Wiley & Sons
  • ISBN: 0470656549
  • Category : Medical
  • Languages : en
  • Pages : 243

Medical Genetics at a Glance covers the core scientific principles necessary for an understanding of medical genetics and its clinical applications, while also considering the social implications of genetic disorders. This third edition has been fully updated to include the latest developments in the field, covering the most common genetic anomalies, their diagnosis and management, in clear, concise and revision-friendly sections to complement any health science course. Medical Genetics at a Glance now has a completely revised structure, to make its content even more accessible. Other features include: • Three new chapters on Gene Identification, The Biology of Cancer, and Genomic Approaches to Cancer • A much extended treatment of Biochemical Genetics • A completely revised chapter on The Cell Cycle, explaining principles of biochemistry and genetics which are fundamental to understanding cancer causation • Two new chapters on Cardiac Developmental Pathology • An extended Case Studies section Providing a broad understanding of one of the most rapidly progressing topics in medicine, Medical Genetics at a Glance is perfect for students of medicine, molecular biology, genetics and genetic counselling, and is a previous winner of a BMA Award.


Perinatal Genetics

Perinatal Genetics

PDF Perinatal Genetics Download

  • Author: Mary E Norton
  • Publisher: Elsevier Health Sciences
  • ISBN: 0323530966
  • Category : Medical
  • Languages : en
  • Pages : 350

Get a quick, expert overview of the fast-changing field of perinatal genetics with this concise, practical resource. Drs. Mary Norton, Jeffrey A. Kuller, Lorraine Dugoff, and George Saade fully cover the clinically relevant topics that are key to providers who care for pregnant women and couples contemplating pregnancy. It’s an ideal resource for Ob/Gyn physicians, maternal-fetal medicine specialists, and clinical geneticists, as well as midwives, nurse practitioners, and other obstetric providers. Provides a comprehensive review of basic principles of medical genetics and genetic counseling, molecular genetics, cytogenetics, prenatal screening options, chromosomal microarray analysis, whole exome sequencing, prenatal ultrasound, diagnostic testing, and more. Contains a chapter on fetal treatment of genetic disorders. Consolidates today’s available information and experience in this important area into one convenient resource.