Theoretical Aspects of Pedigree Analysis

Theoretical Aspects of Pedigree Analysis

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  • Author: Emil Ginsburg
  • Publisher: RAMOT-TEL AVIV UNIVERSITY, ISRAEL
  • ISBN: 9652744247
  • Category : Biometric identification
  • Languages : en
  • Pages : 94


BIOMAT 2010

BIOMAT 2010

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  • Author: Rubem P. Mondaini
  • Publisher: World Scientific
  • ISBN: 9814343439
  • Category : Science
  • Languages : en
  • Pages : 411

This volume contains the selected contributed papers of the BIOMAT 2010 International Symposium which has been organized as a joint conference with the 2010 Annual Meeting of the Society for Mathematical Biology (http: //www.smb.org) by invitation of the Director Board of this Society. The works presented at Tutorial and Plenary Sessions by expert keynote speakers have been also included. This book contains state-of-the-art articles on special research topics on mathematical biology, biological physics and mathematical modelling of biosystems; comprehensive reviews on interdisciplinary areas written by prominent leaders of scientific research groups. The treatment is both pedagogical and sufficiently advanced to enhance future scientific research


BIOMAT 2010

BIOMAT 2010

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  • Author: Rubem P Mondaini
  • Publisher: World Scientific
  • ISBN: 9814460672
  • Category : Science
  • Languages : en
  • Pages : 412

This volume contains the selected contributed papers of the BIOMAT 2010 International Symposium which has been organized as a joint conference with the 2010 Annual Meeting of the Society for Mathematical Biology (http://www.smb.org) by invitation of the Director Board of this Society. The works presented at Tutorial and Plenary Sessions by expert keynote speakers have been also included. This book contains state-of-the-art articles on special research topics on mathematical biology, biological physics and mathematical modelling of biosystems; comprehensive reviews on interdisciplinary areas written by prominent leaders of scientific research groups. The treatment is both pedagogical and sufficiently advanced to enhance future scientific research. Contents:MorphologyMolecular BiophysicsMathematical EpidemiologyPopulation DynamicsPopulation BiologyTheoretical ImmunologyComputational BiologyMathematical Aspects of BioprocessesPopulation GeneticsSystems Biology Readership: Mathematicians, biologists, physicists; graduate and undergraduate students interested in biomathematics. Keywords:Mathematical Biology;Biological Physics;Mathematical Modelling of Biosystems


Pedigree Analysis in R

Pedigree Analysis in R

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  • Author: Magnus Dehli Vigeland
  • Publisher: Academic Press
  • ISBN: 0128245603
  • Category : Law
  • Languages : en
  • Pages : 184

Pedigree Analysis in R gives an introduction to the theory of relatedness and covers a range of applications in forensic and medical genetics. The book's material was developed through teaching courses on genetic relatedness, pedigree analysis and R, and offers insights from a decade of research activities in forensic and medical genetics. The R code in the book uses the ped suite, a unified collection of packages for pedigree analysis, developed by the author. All code examples are given in full, allowing accurate reproduction of figures and results. At the end of each chapter, a selection of exercises encourages the reader to explore further and perform their own analyses. Introduction to the theory of genetic relatedness, richly illustrated with classic and novel examples In-depth case studies including kinship testing, pedigree reconstruction, linkage analysis and clinical segregation analysis Easy-to-follow R code with explanations Based on the ped suite packages for pedigree analysis in R Suitable for R users at all levels, including complete beginners Exercises after each chapter


Annual Report, Intramural Activities

Annual Report, Intramural Activities

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  • Author: National Cancer Institute (U.S.). Division of Cancer Etiology
  • Publisher:
  • ISBN:
  • Category : Cancer
  • Languages : en
  • Pages : 332


Improving How Universities Teach Science

Improving How Universities Teach Science

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  • Author: Carl Wieman
  • Publisher: Harvard University Press
  • ISBN: 0674978927
  • Category : Science
  • Languages : en
  • Pages : 288

Too many universities remain wedded to outmoded ways of teaching. Too few departments ask whether what happens in their lecture halls is effective at helping students to learn and how they can encourage their faculty to teach better. But real change is possible, and Carl Wieman shows us how it can be done—through detailed, tested strategies.


Population Genetics and Microevolutionary Theory

Population Genetics and Microevolutionary Theory

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  • Author: Alan R. Templeton
  • Publisher: John Wiley & Sons
  • ISBN: 1118504364
  • Category : Science
  • Languages : en
  • Pages : 768

Population Genetics and Microevolutionary Theory Explore the fundamentals of the biological implications of population genetic theory In the newly revised Second Edition of Population Genetics and Microevolutionary Theory, accomplished researcher and author Alan R. Templeton delivers a fulsome discussion of population genetics with coverage of exciting new developments in the field, including new discoveries in epigenetics and genome-wide studies. The book prepares students to successfully apply population genetics analytical tools by providing a solid foundation in microevolutionary theory. The book emphasizes that population structure forms the underlying template upon which quantitative genetics and natural selection operate and is a must-read for future population and evolutionary geneticists and those who wish to work in genetic epidemiology or conservation biology. You’ll learn about a wide array of topics, including quantitative genetics, the interactions of natural selection with other evolutionary forces, and selection in heterogeneous environments and age-structured populations. Appendices that cover genetic survey techniques and probability and statistics conclude the book. Readers will also benefit from the inclusion of: A thorough introduction to population genetics, including the scope of the subject, its premises, and the Hardy-Weinberg Model of Microevolution An exploration of systems of mating, including a treatment of the use of runs of homozygosity to show pedigree inbreeding in distant ancestors A practical discussion of genetic drift, including the use of effective sizes in conservation biology (with a discussion of African rhinos as an example) A concise examination of coalescence, including a treatment of the infinite sites model Perfect for graduate students in genetics and evolutionary biology programs and advanced undergraduate biology majors, Population Genetics and Microevolutionary Theory will also earn a place in the libraries of students taking courses in conservation biology, human genetics, bioinformatics, and genomics.


Recent Progress in the Genetic Epidemiology of Cancer

Recent Progress in the Genetic Epidemiology of Cancer

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  • Author: Henry T. Lynch
  • Publisher: Springer Science & Business Media
  • ISBN: 3642759939
  • Category : Medical
  • Languages : en
  • Pages : 162

The discipline of genetic epidemiology pertains to the vertical transmission of the susceptibility (predisposition) to a complex disease in a structured population. This statement meets halfway 1 the broad definitiongiven by N. E. Morton and S. c. Chung in 1978 2 and the concise one given by M. -C. King et al. in 1984. 1t pinpoints the fundamental genetic hypothesis, namely, the existence of an inherited condition that predisposes an individual to a specific disease, and the corresponding subject ofinvestigation, the family. Thus, the genetic epidemiological situation consists of three basic elements: (l) the genealogical structure, (2) the mode of inherit ance (i. e. , the "genetic model") for the trait of interest, and (3) the observable phenotypes of susceptibility. It is clear that genetic epidemiology is a research field posi tioned at the intersection of molecular genetics, population gen etics, and clinical genetics. Perhaps the genealogical tree should be its central element: it evidences something forgotten in mole cular genetics, namely the relationships, and associations with probabilistic and statistical concepts from population genetics. It offers a structure and a "history" for those clinicians studying familial diseases who are searching for genetic determinants of susceptibility. The genetic epidemiologist begins his analysis with a point on this genealogical tree, namely the proband, and attempts to carry out (nonrandom) "ascertainment sampling" by using a strategy that depends on the form and dimension (extended pedigrees versus nuclear families) of the tree.


Research Awards Index

Research Awards Index

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  • Author:
  • Publisher:
  • ISBN:
  • Category : Medicine
  • Languages : en
  • Pages : 1588


Perspectives in Ecological Theory

Perspectives in Ecological Theory

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  • Author: Jonathan Roughgarden
  • Publisher: Princeton University Press
  • ISBN: 1400860180
  • Category : Science
  • Languages : en
  • Pages : 403

This volume presents an overview of current accomplishments and future directions in ecological theory. The twenty-three chapters cover a broad range of important topics, from the physiology and behavior of individuals or groups of organisms, through population dynamics and community structure, to the ecology of ecosystems and the geochemical cycles of the entire biosphere. The authors focus on ways in which theory, whether expressed mathematically or verbally, can contribute to defining and solving fundamental problems in ecology. A second aim is to highlight areas where dialogue between theorists and empiricists is likely to be especially rewarding. The authors are R. M. Anderson, C. W. Clark, M. L. Cody, J. E. Cohen, P. R. Ehrlich, M. W. Feldman, M. E. Gilpin, L. J. Gross, M. P. Hassell, H. S. Horn, P. Kareiva, M.A.R. Koehl, S. A. Levin, R. M. May, L. D. Mueller, R. V. O'Neill, S. W. Pacala, S. L. Pimm, T. M. Powell, H. R. Pulliam, J. Roughgarden, W. H. Schlesinger, H. H. Shugart, S. M. Stanley, J. H. Steele, D. Tilman, J. Travis, and D. L. Urban. Originally published in 1989. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.