Mutation-Driven Evolution

Mutation-Driven Evolution

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  • Author: Masatoshi Nei
  • Publisher: OUP Oxford
  • ISBN: 0191637815
  • Category : Science
  • Languages : en
  • Pages : 256

The purpose of this book is to present a new mechanistic theory of mutation-driven evolution based on recent advances in genomics and evolutionary developmental biology. The theory asserts, perhaps somewhat controversially, that the driving force behind evolution is mutation, with natural selection being of only secondary importance. The word 'mutation' is used to describe any kind of change in DNA such as nucleotide substitution, gene duplication/deletion, chromosomal change, and genome duplication. A brief history of the principal evolutionary theories (Darwinism, mutationism, neo-Darwinism, and neo-mutationism) that preceded the theory of mutation-driven evolution is also presented in the context of the last 150 years of research. However, the core of the book is concerned with recent studies of genomics and the molecular basis of phenotypic evolution, and their relevance to mutation-driven evolution. In contrast to neo-Darwinism, mutation-driven evolution is capable of explaining real examples of evolution such as the evolution of olfactory receptors, sex-determination in animals, and the general scheme of hybrid sterility. In this sense the theory proposed is more realistic than its predecessors, and gives a more logical explanation of various evolutionary events. Mutation-Driven Evolution is suitable for graduate level students as well as professional researchers (both empiricists and theoreticians) in the fields of molecular evolution and population genetics. It assumes that the readers are acquainted with basic knowledge of genetics and molecular biology.


Mutation-Driven Evolution

Mutation-Driven Evolution

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  • Author: Masatoshi Nei
  • Publisher: OUP Oxford
  • ISBN: 0191637823
  • Category : Science
  • Languages : en
  • Pages : 256

The purpose of this book is to present a new mechanistic theory of mutation-driven evolution based on recent advances in genomics and evolutionary developmental biology. The theory asserts, perhaps somewhat controversially, that the driving force behind evolution is mutation, with natural selection being of only secondary importance. The word 'mutation' is used to describe any kind of change in DNA such as nucleotide substitution, gene duplication/deletion, chromosomal change, and genome duplication. A brief history of the principal evolutionary theories (Darwinism, mutationism, neo-Darwinism, and neo-mutationism) that preceded the theory of mutation-driven evolution is also presented in the context of the last 150 years of research. However, the core of the book is concerned with recent studies of genomics and the molecular basis of phenotypic evolution, and their relevance to mutation-driven evolution. In contrast to neo-Darwinism, mutation-driven evolution is capable of explaining real examples of evolution such as the evolution of olfactory receptors, sex-determination in animals, and the general scheme of hybrid sterility. In this sense the theory proposed is more realistic than its predecessors, and gives a more logical explanation of various evolutionary events. Mutation-Driven Evolution is suitable for graduate level students as well as professional researchers (both empiricists and theoreticians) in the fields of molecular evolution and population genetics. It assumes that the readers are acquainted with basic knowledge of genetics and molecular biology.


Biogeography and Evolution in New Zealand

Biogeography and Evolution in New Zealand

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  • Author: Michael Heads
  • Publisher: CRC Press
  • ISBN: 1315351218
  • Category : Science
  • Languages : en
  • Pages : 652

Biogeography and Evolution in New Zealand provides the first in-depth treatment of the biogeography of New Zealand, a region that has been a place of long-enduring interest to ecologists, evolutionary scientists, geographers, geologists, and scientists in related disciplines. It serves as a key addition to the contemporary discussion on regionalization—how is New Zealand different from the rest of the world? With what other areas does it share its geology, history, and biota? Do new molecular phylogenies show that New Zealand may be seen as a biological ‘parallel universe’ within global evolution?


Evolutionary mechanisms of infectious diseases, volume II

Evolutionary mechanisms of infectious diseases, volume II

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  • Author: Jianying Gu
  • Publisher: Frontiers Media SA
  • ISBN: 2832521924
  • Category : Science
  • Languages : en
  • Pages : 135


Growth Regulation and Carcinogenesis

Growth Regulation and Carcinogenesis

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  • Author: Walter R. Paukovits
  • Publisher: CRC Press
  • ISBN: 1351089226
  • Category : Science
  • Languages : en
  • Pages : 326

Growth Regulation and Carcinogenesis discusses topics such as growth factors, including stimulators and inhibitors of proliferation; networks in proliferation regulation; differentiation-inducing factors; origins of neoplasia and their relationship to growth control; genetic alterations in cellular regulatory machinery; extrachromosomal phenomena; non-genotoxic carcinogens; immortalization and transformation of cells; and the role of cell production, cell function, and cell elimination in physiological growth control.


Evolutionary Biology: Biodiversification from Genotype to Phenotype

Evolutionary Biology: Biodiversification from Genotype to Phenotype

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  • Author: Pierre Pontarotti
  • Publisher: Springer
  • ISBN: 3319199323
  • Category : Science
  • Languages : en
  • Pages : 409

This book presents 20 selected contributions to the 18th Evolutionary Biology Meeting, which took place in September 2014 in Marseille. They are grouped under the following major themes: · Genotype to Phenotype · Genetic Mechanisms of Diversification · Evolutionary Mechanisms · Speciation and Biodiversity The aims of these annual meetings in Marseille are to bring together leading evolutionary biologists and other scientists who employ evolutionary biology concepts, e.g. for medical research, and to promote the exchange of ideas and encourage interdisciplinary collaborations. Offering an up-to-date overview of recent advances in the field of evolutionary biology, this book represents an invaluable source of information for scientists, teachers and advanced students.


Evolutionary Biology: Contemporary and Historical Reflections Upon Core Theory

Evolutionary Biology: Contemporary and Historical Reflections Upon Core Theory

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  • Author: Thomas E. Dickins
  • Publisher: Springer Nature
  • ISBN: 3031220285
  • Category : Science
  • Languages : en
  • Pages : 606

This book is reflecting upon core theories in evolutionary biology – in a historical as well as contemporary context. It exposes the main areas of interest for discussion, but more importantly draws together hypotheses and future research directions. The Modern Synthesis (MS), sometimes referred to as Standard Evolutionary Theory (SET), in evolutionary biology has been well documented and discussed, but was also critically scrutinized over the last decade. Researchers from diverse disciplinary backgrounds have claimed that there is a need for an extension to that theory, and have called for an Extended Evolutionary Synthesis (EES). The book starts with an introductory chapter that summarizes the main points of the EES claim and indicates where those points receive treatment later in the book. This introduction to the subjects can either serve as an initiation for readers new to the debate, or as a guide for those looking to pursue particular lines of enquiry. The following chapters are organized around historical perspectives, theoretical and philosophical approaches and the use of specific biological models to inspect core ideas. Both empirical and theoretical contributions have been included. The majority of chapters are addressing various aspects of the EES position, and reflecting upon the MS. Some of the chapters take historical perspectives, analyzing various details of the MS and EES claims. Others offer theoretical and philosophical analyses of the debate, or take contemporary findings in biology and discuss those findings and their possible theoretical interpretations. All of the chapters draw upon actual biology to make their points. This book is written by practicing biologists and behavioral biologists, historians and philosophers - many of them working in interdisciplinary fields. It is a valuable resource for historians and philosophers of biology as well as for biologists. Chapters 8, 20, 22 and 33 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.


Mutation, Randomness, and Evolution

Mutation, Randomness, and Evolution

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  • Author: Arlin Stoltzfus
  • Publisher: Oxford University Press
  • ISBN: 019884445X
  • Category : Science
  • Languages : en
  • Pages : 283

What does it mean to say that mutation is random? How does mutation influence evolution? Are mutations merely the raw material for selection to shape adaptations? The author draws on a detailed knowledge of mutational mechanisms to argue that the randomness doctrine is best understood, not as a fact-based conclusion, but as the premise of a neo-Darwinian research program focused on selection. The successes of this research program created a blind spot - in mathematical models and verbal theories of causation - that has stymied efforts to re-think the role of variation. However, recent theoretical and empirical work shows that mutational biases can and do influence the course of evolution, including adaptive evolution, through a first come, first served mechanism. This thought-provoking book cuts through the conceptual tangle at the intersection of mutation, randomness, and evolution, offering a fresh, far-reaching, and testable view of the role of variation as a dispositional evolutionary factor. The arguments will be accessible to philosophers and historians with a serious interest in evolution, as well as to researchers and advanced students of evolution focused on molecules, microbes, evo-devo, and population genetics.


Proceedings

Proceedings

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  • Author:
  • Publisher:
  • ISBN:
  • Category : Microwave devices
  • Languages : en
  • Pages : 696


The Evolutionary Biology of Viruses

The Evolutionary Biology of Viruses

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  • Author: Stephen S. Morse
  • Publisher: Lippincott Williams & Wilkins
  • ISBN:
  • Category : Evolution
  • Languages : en
  • Pages : 376