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This volume in Advances in Pharmacology focuses on all aspects of catecholamine research, from very basic to medical. It is broad based and covers many areas within physiology and medicine.
This book is based on invited presentations at the Ninth International Catecholamine Symposiwn. Over several decades, each International Catecholamine Symposiwn (ICS) has provided a uniquely important forwn for updating basic as well as clinical research on the catecholamines, dopamine, norepinephrine, and epinephrine. The first ICS took nd n1 place in Bethesda, Maryland, in the USA in 1958; the 2 in Milan, Italy in 1965; the 3 th in Strasbourg, France in 1973; the 4th in Asilomar, California, USA in 1978; the 5 in th th Goteborg, Sweden in 1983; the 6 in Jerusalem, Israel,in 1987; the 7 in Amsterdam, th Netherlands in 1992; and the 8 in Asilomar, California, USA in 1996. th The 9 International Catecholamine Symposiwn (9ICS) was held in Kyoto, Japan, th March 31-April 5, 2001. This ICS was held concurrently with the 5 International th Conference on Progress in Alzheimer's and Parkinson's Disease (5 ADPD). These international meetings were coordinated to be a joint international congress. Catecholamines and related neurotransmitters and neuromediators play important roles in the pathogenesis of symptoms and neurodegenerative processes of Alzheimer's disease and Parkinson's disease. Therefore, the Joint Congress provided an opportunity for investigators and clinicians working in these fields to exchange their· most recent investigational results and clinical experiences. This Joint International Congress turned out to be an enormous success, attended by 1258 participants from 38 countries, in an enthusiastic and pleasant atmosphere.
Deriving the latest material from the Seventh Symposium on Catecholamines and other Neurotransmitters in Stress held in the Slovak Republic, Stress: Neural, Endocrine and Molecular Studies presents some of the latest research into stress, focusing on catecholamines and other neurotransmitter molecules. Topics covered include: Peripheral
Volume 95 of International Review of Neurobiology focuses on Catechol-O-methyltransferase inhibition, and its clinical application in relation to Parkinson’s disease. Chapters cover COMT gene and proteins, L-dopa treatment in Parkinson’s disease, the latest research on COMT inhibitors and their clinical applications, as well as future prospects for their use. Up-to-date summary of biochemistry and pharmacology of COMT and its inhibitors Preclinical models in COMT inhibitor devlopment Transgenic COMT mice – latest information summarized Chemistry of COMT inhibitors and their design with molecular modelling COMT gene and its regulation and relation to dopamine related diseases Role of cofactor SAM regulation in relation to homocysteine Nonclinical and clinical safety of COMT inhibitors summarized Future prospects of COMT inhibitors in Parkinson’s disease
Multiple subtypes of dopamine receptors exist in the brain. This volume reviews the characteristics of D-1, D-2, D-3 and D-4 receptors and describes the current concepts of their involvement in motor disorders and in the control of schizophrenia. Readers: the book will be of great interest to professionals in pharmacology, medicinal chemistry, neuroscience, cell biology and therapeutic applications in clinical medicine as antipsychotics, anti-Parkinson's disease and related areas.
Widely regarded as the authoritative work in the field, this book comprehensively explores the psychological needs of today's service members and how to meet them effectively. Expert contributors review best practices for conducting fitness-for-duty evaluations and other types of assessments, treating frequently encountered clinical problems, responding to disasters, and promoting the health and well-being of all personnel. The book also examines the role of mental health professionals in enhancing operational readiness, with chapters on crisis and hostage negotiation, understanding terrorists, and more. New to This Edition *The latest scientific knowledge, clinical interventions, and training recommendations. *Chapter on acute combat stress. *Chapter on post-deployment problems, including PTSD and depression. *Chapter on military psychology ethics. *Coverage of blast concussion screening and evaluation. ?
Edited by Benjamin L. Hankin and John R. Z. Abela, Development of Psychopathology: A Vulnerability-Stress Perspective brings together the foremost experts conducting groundbreaking research into the major factors shaping psychopathological disorders across the lifespan in order to review and integrate the theoretical and empirical literature in this field. The volume editors build upon two important and established research and clinical traditions: developmental psychopathology frameworks and vulnerability-stress models of psychological disorders.
Essential hypertension (EH) is the most common type of high blood pressure and is responsible for much death and serious illness, which has been the reason for the huge research effort to determine its causes. However, countless scientific articles still keep proclaiming that "the causese of essential hypertension remain unknown." In view of the number of publications that descend on the hypertension specialist like a waterfall, such proclamations seem to overlook the considerable amount of knowledge that we already have about the etiology of EH. The problem may be a lack of synthesis rather than a lack of information. This book brings together some of this knowledge into a coherent and clinically relevant account about the pathogenesis of EH. With an extremely broad reach, this book aims to give a balanced view of the causes of EH, its neural, genetic, and environmental causes.
Biomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry.
