Basic and Clinical Science of Opioid Addiction

2003-01-01
Basic and Clinical Science of Opioid Addiction

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  • Author: Marcus F. Kuntze
  • Publisher: Karger Medical and Scientific Publishers
  • ISBN: 3805575041
  • Category : Medical
  • Languages : en
  • Pages : 80

For the first time reports on methadone and heroin maintenance treatment with respect to clinical practice, research, methodological aspects, neuroscience and psychotherapy are brought together in this volume. They arise from a conference held in November 2001 in Basel. The Swiss approach of a highly structured outpatient treatment using methadone, heroin, morphine etc. to keep patients in treatment is discussed. Data of follow-up after heroin-assisted treatment is shown. Also a critical discussion of the history of treatment modalities and its scientific evaluation is presented. Further important topics such as brain imaging, opioid withdrawal, risks of treatment, and basic neurochemical research are presented. The issue concludes with the narrative experience of a practicing psychotherapist. This topical and outstanding overview gives psychiatrists, psychologists and psychotherapists, neuroscientists, physicians as well as decision makers in public health, politicians, counselors and social workers an excellent insight into stimulating and scientific research.

Pain Management and the Opioid Epidemic

2017-09-28
Pain Management and the Opioid Epidemic

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  • Author: National Academies of Sciences, Engineering, and Medicine
  • Publisher: National Academies Press
  • ISBN: 0309459575
  • Category : Medical
  • Languages : en
  • Pages : 483

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Drugs, Brains, and Behavior

2007
Drugs, Brains, and Behavior

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  • Author:
  • Publisher:
  • ISBN:
  • Category : Brain
  • Languages : en
  • Pages : 76

Medications for Opioid Use Disorder Save Lives

2019-06-16
Medications for Opioid Use Disorder Save Lives

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  • Author: National Academies of Sciences, Engineering, and Medicine
  • Publisher: National Academies Press
  • ISBN: 0309486483
  • Category : Medical
  • Languages : en
  • Pages : 175

The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Clinical Methods

1990
Clinical Methods

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  • Author: Henry Kenneth Walker
  • Publisher: Butterworth-Heinemann
  • ISBN:
  • Category : Medical
  • Languages : en
  • Pages : 1128

A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR

Opioid Dependence

2017-10-07
Opioid Dependence

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  • Author: Heath B. McAnally
  • Publisher: Springer
  • ISBN: 3319474979
  • Category : Medical
  • Languages : en
  • Pages : 301

The book begins with a public health/epidemiologic examination of the situation, with a systematic view of the problem based on classic (infectious disease) epidemiologic principles applied to this behavioral health issue. This application is expanded to take into account the fact that unlike most epidemics in our species’ history, a unique factor that must be accounted for in any public health analysis is that the host (opioid-dependent/misusing patient) is generally not under sufficiently strong motivation to avoid the disease. The introduction concludes with a survey of recent containment approaches, categorized epidemiologically by target (agent, vector, host.) The remainder of the book is organized according to this framework, addressing agent, vector/transmission and host, respectively. Sections Three and Four comprise the major focus of the book, and are dedicated primarily to practical education for primary care providers in preventing opioid use disorder, and overcoming it after the fact.

Improving the Quality of Health Care for Mental and Substance-Use Conditions

2006-03-29
Improving the Quality of Health Care for Mental and Substance-Use Conditions

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  • Author: Institute of Medicine
  • Publisher: National Academies Press
  • ISBN: 0309133661
  • Category : Medical
  • Languages : en
  • Pages : 528

Each year, more than 33 million Americans receive health care for mental or substance-use conditions, or both. Together, mental and substance-use illnesses are the leading cause of death and disability for women, the highest for men ages 15-44, and the second highest for all men. Effective treatments exist, but services are frequently fragmented and, as with general health care, there are barriers that prevent many from receiving these treatments as designed or at all. The consequences of this are seriousâ€"for these individuals and their families; their employers and the workforce; for the nation's economy; as well as the education, welfare, and justice systems. Improving the Quality of Health Care for Mental and Substance-Use Conditions examines the distinctive characteristics of health care for mental and substance-use conditions, including payment, benefit coverage, and regulatory issues, as well as health care organization and delivery issues. This new volume in the Quality Chasm series puts forth an agenda for improving the quality of this care based on this analysis. Patients and their families, primary health care providers, specialty mental health and substance-use treatment providers, health care organizations, health plans, purchasers of group health care, and all involved in health care for mental and substanceâ€"use conditions will benefit from this guide to achieving better care.

Fighting the Opioid Epidemic

2020-07-22
Fighting the Opioid Epidemic

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  • Author: Amitava Dasgupta
  • Publisher: Elsevier
  • ISBN: 0128223901
  • Category : Medical
  • Languages : en
  • Pages : 160

Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic. This succinct reference highlights how the toxicology laboratory can play a vital role in fighting the opioid epidemic by implementing a robust system for drugs of abuse testing as well as drug testing in pain management patients. It targets health care professionals in a technical manner, discussing polymorphisms of important genes that may be associated with increased vulnerability of alcohol and drug addiction to an individual. Covers all important aspects of opioid abuse, including genetic and environmental factors Discusses pharmacology, toxicology and the pharmacogenomics related to opioid metabolism Presents genetic and environmental factors associated with those vulnerable to opioid addiction, as well as the pitfalls of drug testing in pain management

The Opioid Epidemic

2019
The Opioid Epidemic

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  • Author: Yngvild Olsen
  • Publisher: What Everyone Needs to Know(r
  • ISBN: 0190916036
  • Category : Medical
  • Languages : en
  • Pages : 345

An incisive, essential guide to understanding one of today's most urgent -- and complex -- problems. The Opioid Epidemic: What Everyone Needs to Know® is an accessible, nonpartisan overview of the causes, politics, and treatments tied to the most devastating health crisis of our time. Its comprehensive approach and Q&A format offer readers a practical path to understanding the epidemic from all sides. Written by two expert physicians and enriched with stories from their experiences on the front lines of this epidemic, this book is a critical resource for any general reader -- and for the individuals and families fighting this fight in their own lives.

Dispelling the Myths About Addiction

1997-11-10
Dispelling the Myths About Addiction

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  • Author: Institute of Medicine
  • Publisher: National Academies Press
  • ISBN: 0309174597
  • Category : Medical
  • Languages : en
  • Pages : 236

Every year about half a million men, women, and children in the United States die from the effects of using nicotine, alcohol, and illegal drugs: one of every four American deaths. Yet research to solve this terrible problem is often perceived as less important than other types of biomedical investigation. Focusing on four major classes of drugs with the greatest social and economic impactâ€"nicotine, alcohol, opioids, and stimulantsâ€"Dispelling the Myths About Addiction examines what is known about addiction and what is needed to develop a talented cadre of investigators and to educate the public about addiction research. The committee explores these areas: Economic costs of addiction. What has been learned about addiction from research into basic neurobiology and the brain, psychosocial and behavioral factors, and epidemiology. Education and training of researchers and the research infrastructure. Public perceptions and their impact on public policy in this field. This volume outlines the challenges and opportunities in addiction research today and makes recommendations to educators, treatment professionals, public and private institutions, and others for how to build support for addiction research and treatment.